FACTS ABOUT FENTANYL OPIOID EPIDEMIC REVEALED

Routinely evaluate patients, significantly when initiating and titrating dose and when given concomitantly with other drugs that depress respiration; alternatively, consider usage of non-opioid analgesics in these patientsWatch Intently (two)primidone will lower the level or effect of fentanyl by affecting hepatic/intestinal enzyme CYP3A4 metabolis